The Complexity Map of the Human DNA. Is it possible?

The human genome contains 20000-25000 genes (3 billion letters). The approximate number of atoms necessary to encode human DNA is 200 billion. For example, Thymine’s base is a pyrimidine ring compound and it contains 15 atoms. Its pentose sugar has 15 atoms also (the 5-carbon sugar used for ribonucleic acid (RNA) is very similar, but…

Who Rates Ratings?

  The economy is a dynamic system which is far too complex for us to understand. Human nature is extremely complex and billions of irrational humans form the economy. How can such a system ever be thought to be efficient, in equilibrium and stable, as many prominent economists have claimed? But this system, like every…

Building a “Complexity Management Device”

  Arduino is an open-source electronics platform based on easy-to-use hardware and software. It’s intended for anyone making interactive projects, see TED video. Arduino boards (see list here) come in numerous types and may be connected to a wide variety of inputs (sensors, devices) and outputs (actuators, devices, computers). For example, the Arduino Fio boardis…

Complexity-Based Estimation of Drug Toxicity

As the patents on many drugs, which have been launched in the 1990s, will soon expire, the pharmaceutical industry finds itself at a turning point in its evolution, particularly as far as research and development are concerned. As the pipelines of new products are shrinking, the exposure of many companies is increasing. This will surely…

Amazing what Complexity Technology can do for Medicine

  Even though the so-called “complexity science” has been around for a few decades, it has failed to produce workable definitions and metrics of complexity. In fact, complexity still today is being seen as a series of phenomena of un-orchestrated self-organization (e.g. swarms of starlings), and emergence in which their complexity is never measured. In…

Complexity Science Helps in Early-detection of Fibrillations and Tachyarrhythmia

The main goal of ONTONET-CRT™ is to reduce detection times as well as unnecessary ICD shocks. ONTONET-CRT™ adopts new model-free technology which does not rely on traditional math models. Instead of conventional analysis ONTONET-CRT™ processes the EGM and computes its complexity. Its sudden fluctuations generally anticipate events such as fibrillations or tachycardias. ONTONET-CRT™ processing of…